ESO Has Strong Silver and Pathfinder Results Associated With Gold Mineralization in First Drill Program on Donna Gold, BC Project

VANCOUVER, BRITISH COLUMBIA -- (Marketwire) -- 10/28/10 -- ESO Uranium Corp. (TSX VENTURE: ESO)(FRANKFURT: E2G) (the 'Company' or 'ESO') is pleased to announce results of silver and pathfinder element assays in a seven (7) hole, 850 meter drill program on the Donna Gold Property, in South Central British Columbia.

Elevated silver and pathfinder element results are consistent with a strongly anomalous gold zone that extends west from the trenching and is open (as yet undrilled) further to the west along the soils anomaly (described in the news release of October 6th, 2010). Highlights of the silver assays include:

--  Elevated silver values are associated with gold mineralization in 6 out
    of 7 drill holes as broad anomalous zones (greater than 2.0 g/t silver)
    with higher grade veining.

--  DDH10-4 intersected 0.5 meters of 287 g/t silver within a vein system 3
    meters at approximately true width, grading 51.9 g/t silver.

--  Drill Hole            Depth m    Ag zone metres   Grade g/t Ag
    --------------------------------------------------------------
    DDH10-5          23.4 - 44.60              21.2           2.41

    DDH10-4          11.7 - 42.50              30.8          11.85
    Including         14.0 - 17.0               3.0          51.85
    Including        24.25 - 29.6              5.35          36.38
    And               62.7 - 66.0               3.3          19.36

    DDH10-3          12.3 - 24.35             12.05           0.32

    DDH10-2          10.5 - 37.20              26.7           0.41
    And              47.0 - 74.80              27.8           0.96

    DDH10-1           7.0 - 64.70              57.7           3.69
    Including         10.4 - 17.0               6.6          17.18

Pathfinder elements that showed an association with the gold - silver zones included a population of anomalous copper, lead, and zinc whole rock values, and a second population with anomalous antimony, zinc, and arsenic whole rock values. These values are reflected in stream sediment and soil sample geochemical anomalies shown in the earlier regional and detailed sampling programmes. The two populations of pathfinder elements suggest that gold was emplaced in multiple mineralizing events.

ESO management is very encouraged with this initial drill program as it confirmed gold-silver mineralization targeted on the western side of earlier trenching and the gold anomaly in soils that extends more than 1,600 meters (5,300 feet) along the height of land between the Kettle River and Yeoward Creek. Both of these are historical gold placer producers with their source rock being in the area being tested.

The multi-element analyses were carried out by ALS Laboratory Group, an ISO 17025 minerals assay laboratory. The 33 element analysis was done on each sample with a four acid digestion followed by ICP-MS techniques (ALS Group ME-ICP61).

A further drill program is planned, targetting a bulk tonnage gold/silver deposit that is to be hosted by the quartz stockwork veining, metasediments and the dioritic dikes.

In addition a, winter drill program is planned for the Mikwam (Ontario) Gold project in view of the continuing strong price of the metal. At current prices, a gram of gold sells for approximately US$42.

B. Ainsworth, PEng BC, is the Qualified Person responsible for the technical disclosure contained in this news release.

On behalf of the Board of Directors of ESO Uranium Corp.

Ben Ainsworth, Vice President, Exploration

This news release includes certain statements that express management's expectation or estimates of future performance and may be deemed 'forward-looking statements'. These forward-looking statements include plans, estimates, forecasts and statements as to management's expectations regarding its mineral properties. These forward-looking statements involve assumptions, risks and uncertainties and actual results may vary materially. For these reasons shareholders should not place undue reliance on such forward-looking information.

United States residents are cautioned that some of the information that may be published by ESO Uranium Corp. may not be consistent with United States Securities and Exchange Commission disclosure rules and may be materially different from what the Company is permitted to disclose in the United States and therefore United States residents should not rely on such information.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contacts:

ESO Uranium Corp. - Corporate Communications

Robert (Bob) Meister

(604) 629-0293 or Toll Free: 1-866-629-8368

(604) 684-9365 (FAX)
info@esouranium.com
www.esouranium.com